Three bodies had head and chest injuries consistent with intense force similar to that of a car crash. "[7], Grant's conclusions and speculations about the incident were evaluated by professional forensic scientists, chemists, and toxicologists, passed peer review in an accredited, refereed journal, and were published by Forensic Science International. The most severe case required two weeks of hospitalization. Users of this substance report that it has a garlic-like taste. The clothes of whoever could have been exposed were removed into plastic bags. The only thing unusual about her was her age, recalls Maureen Welch, a respiratory therapist who was assisting in the trauma room that night. Other scientists dont see a match between the symptoms of the hospital staff and some of the symptoms of industrial workers who have been accidentally exposed to dimethyl sulfate. Sooez 18 Pack Plastic File Folders Colored with Sticky Labels, Letter Size Colored File Folders with Erasable 1/3-Cut Tab, Stronger Than Manila File Folder, Perfect for Organization, Assorted Color. There were multiple reports from locals that they had spotted the Sodder children in the years following the fire and a letter came to the family in 1968 claiming to be from a surviving son. Doctors quickly got to work trying to save her life, but nothing seemed to be working. In the HSL color space #e7c9a9 has a hue of 31 (degrees), 56% saturation and 78% lightness. The team was supposed to come back by February 12th, and a search party of their classmates and teachers were sent out to look for them on the 20th. Im pretty skeptical, says Hans Reich, an organic chemist at the University of Wisconsin at Madison. The conclusion: The hospital staff most likely experienced an outbreak of mass sociogenic illness, perhaps triggered by an odor. When they cooled a vial of this Ringers solution crammed with dimethyl sulfone to room temperature (about 70 degrees), they were greeted by a good sign. An emergency room entrance. In fact, Jacob says, the Livermore scientists should never have allowed the Riverside coroner to release their report. On February 21st, Lams body was found on the roof of the hotel in a water tank. Georges ladder was missing. The town reportedly jumped on this theory, selling a vodka gelatin jellyfish drink at the local bar. When oxygen was added, it could have become dimethyl sulfone, forming the crystals in Ramirezs blood. About 8:15p.m. on the evening of February 19, 1994, Ramirez, suffering from severe heart palpitations, was brought into the emergency department of Riverside General Hospital in Riverside, by paramedics. Source: Wikipedia commons This theory has been endorsed by the Riverside Coroner's Office and published in the journal Forensic Science International. The second communication gave supplemental support for the postulated chemical scenario as well as insight into some of the sociology and vested interests inherent in the case.[specify]. Dimethyl sulfate doesnt vaporize easily the Merck Index lists its boiling point as 370 degrees. The health departments report triggered another flurry of news reports; these featured Gorchynski and her lawyer, physician Russell Kussman, who denounced the mass hysteria conclusion. For now, researchers cant find a similar poisoning in the medical annals, nor can they say whether hospitals should fret about future cases. At 8.50 PM, after 45 minutes of CPR and defibrillation, she was pronounced dead due to kidney failure. A total of 23 staff became sick after exposure, and 5 were hospitalized. She was sedated and then defibrillated by doctors, who noticed that her body was covered in an oily sheen. But given its potential side effects, its a dangerous remedy because in its readily available hardware- store grease-cutting form, its 99 percent pure. That would account for the oily sheen and garlicky odor observed by the staff. Oxygen molecules flooded her bloodstream, combining with the DMSO in her system, the researchers hypothesized, to form high levels of dimethyl sulfone. The procedure was as follows: First Andresen inserted a drop of a prepared sample into the chromatograph. We found we could load it up in the Ringers solution to an appreciable extent without any sweat, says Grant. Up to 600 dogs may have died this way, prompting theories that a supernatural presence may be at play. At 1:00 a.m., she heard an object hit the roof and roll but she went back to sleep. Fearing that a DMSO drug might ruin peoples eyesight, the Food and Drug Administration ordered companies to cease clinical trials of the drug in 1965. Kane turned toward the door of the trauma room and swayed. As for the illness in the hospital workers and how that might be linked to Ramirez, Hill concluded that exhaustive toxicological studies have not identified any external toxic substances that would have contributed to her death. A bare minimum of staff remained to stabilize Gloria Ramirez. Meanwhile, back in trauma one, Welch became the third to succumb. However, a former hotel employee endorsed the theory and said that helicopters were known to fly low over the hotel, despite the airspace rules. Its like that silliness with cold fusion, except this has the potential to hurt people, he says. Test with samples. Something wasn't right with the patient and it had nothing to do with heart failure. She fainted after handing the syringe to a medical resident, Julie Gorchynski, and was taken out of the room. The truth behind Lams death, however, remains a mystery. One was an unidentified amine, a derivative of ammonia, that may have contributed to the ammonia-like smell noted in the emergency room. There were also injuries on the back of her head consistent with blunt force, and the coroner stated that he believed she had not died from a fall, but may have been beaten. They dissolved the compound in a transparent liquid called Ringers solution, which is basically all the ingredients of blood minus red blood cells. Two staff members moved the body to an isolation anteroom adjacent to trauma one. They interviewed 34 hospital staff who had been working in the emergency room on February 19. [2] Sold in gel form at hardware stores, it could also explain the greasy appearance of Ramirez's body. As if the situation wasnt strange enough already, suddenly, one after the other, nurses in the room started to faint. When Ramirez collapsed (presumably from cancer-related kidney failure) and was put in an ambulance, the paramedics put an oxygen mask on her face. This is likely to occur again DMSO is not uncommon, asserts Barry Taylor, a microbiologist at Loma Linda University School of Medicine who has followed the case closely. The tent was sliced open from the inside. Vapors of dimethyl sulfate, the index explained, kill cells in exposed tissues, such as the eyes, mouth, and lungs. Livermore, situated about 60 miles east of San Francisco, is rooted in the nuclear arms buildup that started shortly after World War II. Next Andresen analyzed the samples using a high-powered tool known as a computer-guided combined gas chromatograph-mass spectrometer. A third odd chemical signal defied being pigeonholed as either trivial or important: dimethyl sulfone. Reich doubts that dimethyl sulfone would split apart in the human bodys relatively cool environment. Andresens team had a more likely explanation for the amine, though: they said it formed as Ramirezs body broke down the antinausea drug Tigan. The Mysterious Disappearance Of The Sri Lankan Handball Team. Nevertheless, he thinks the hypothesis is a good one. To obtain blood for analysis, a registered nurse named Susan Kane swabbed Ramirezs right arm with rubbing alcohol, inserted a catheter, and attached a syringe. It is also very expensive, being several times more expensive than woodpulp, hence the change to that fiber for what is still called Manillausually with two Ls. Grant was more familiar with dmso because, he says, Id used dmso in a former life as an athlete. A skeleton crew stayed behind to help him in a desperate struggle to save Ramirezs life. At around 11 PM, a hazardous materials team from Riverside County arrived and started looking for known volatile toxins, including hydrogen sulfide, but found none. . Get unlimited access for as low as $1.99/month. Soon she was in such bad shape that she too was laid out on a gurney. With the rise of internet sleuths, true crime podcasts and videos, and discussion forums, its safe to say that many people love speculating about real-life mysteries. [8][9] The first paper was technically detailed and contained two potential chemical reaction mechanisms that may possibly have formed dimethyl sulfate from dimethyl sulfoxide and dimethyl sulfone precursors. At the time he died, Rivera seemed to be happily married and pursuing his dream of becoming a screenwriter. Others were concerned it could be a strange science experiment that had been released on the town. This was the gas that poisoned the emergency room staff. But other factors that correlated with severe symptoms did not appear to match a scenario in which fumes had been released: the survey found that those afflicted tended to be women rather than men, and they all had normal blood tests after the exposure. [4] The Livermore scientists postulated on The New Detectives that the change in temperature of the blood drawn, from the 98.6F (37C) of Ramirez's body to the 64 F (18C) of the emergency department, may have contributed to its conversion from DMSO2 into DMSO4. All in all, officials conducted three autopsies on Ramirezs body and concluded that she died of heart failure due to kidney failure brought on by her late-stage cancer. CD Bioparticles provide a wide range of uniform and monodisperse colored polystyrene particles. Manila is most commonly used for making file folders[1] and envelopes, called Manila folders and Manila envelopes, respectively. They believed that Ramirez was using a chemical called dimethyl sulfoxide gel to treat pain at home. Gloria Ramirezs life was pretty normal but the circumstances surrounding her bizarre death have made her one of historys weirdest people. It is just as strong as kraft paper but has better printing qualities, such as stronger pigment retention. Grant was a bit hesitant. Adapted from Sheng, 2017. You can help Wikipedia by expanding it. It takes a really damn potent toxin to do all that, says Sheldon Wagner, a clinical toxicologist at Oregon State University. Medical staff also noticed a strange fruity garlic scent on her breath and manila-colored particles floating in Ramirez's blood. But other factors that correlated with severe symptoms didnt seem to match a scenario in which fumes had been released: the survey found that those afflicted tended to be women rather than men, as well as people who had skipped dinner that evening rather than those who had a full stomach. George and Jeannie Sodder were Italian immigrants who lived with their ten children in Fayetteville, West Virginia, an area with many other Italian families. An investigation by local scientists found human white blood cells in the material, leading to the idea that the blobs were at least once a living material. If Andresens team is right, one has to wonder whether the outbreak was unique. In early October, when the Livermore scientists took up the Ramirez case again, they first had to decide whether her body could have generated the dimethyl sulfate. An investigation by Lawrence Livermore National Laboratory proposed that Ramirez had been self-administering dimethyl sulfoxide as a treatment for pain, which converted into dimethyl sulfate, an extremely poisonous and highly carcinogenic alkylating agent, via a series of chemical reactions in the emergency department. Grant decided to find out more about DMSO and dimethyl sulfone, so when he got back to Livermore he looked up the two compounds in the Merck Index, a chemists bible that describes the characteristics of more than 10,000 chemicals, drugs, and biological substances. That could have aggravated the buildup of dimethyl sulfone by preventing it from being flushed out of her system.). She had been admitted to the emergency department while suffering from late-stage cervical cancer. A trained forensic eye can quickly dismiss such misleading signals. Despite the hospital teams best efforts, Ramirez died that night. The hospital was evacuated except for a few people staying to help Ramirez, but she died forty-five minutes after she arrived at the hospital from complications of cancer. Alarmed by the growing cult of DMSO users, the FDA issued a warning to physicians in 1980: Counsel patients against purchasing dmso of unknown quality and medicating themselves. In addition, they pointed out, neither paramedic who had treated Ramirez in the ambulance became ill despite the close quarters and their having touched her skin and some of her blood after starting an intravenous line. It incorporated all that was known about subatomic particles at the time and predicted the existence of additional particles as well. The researchers could think of two scenarios that would explain how Ramirez had been exposed to DMSO. Manila envelopes are great for more than just businesses. Alcohol was also found in her system. Since nicotinamide is relatively inexpensive and can cause euphoria, dealers can extend their expensive drugs with it and make a larger profit. Matching Colors Simply White 2143-70 Add to Cart Shopping List The staff was then ordered to evacuate all emergency department patients to the parking lot outside the hospital. Her blood also alarmingly smelled like ammonia. In all, 23 of the 37 emergency room staff members experienced at least one symptom. [2], Manila paper was originally made out of old Manila hemp ropes which were extensively used on ships, having replaced true hemp. Gorchynski had to spend two weeks in intensive care and use crutches for two months. One thing that particularly struck him was a speculation in the autopsy report about the source of the garlicky odor of Ramirezs body and its oily sheen: DMSO. George and Jeannie believed that their five missing children did not die in the fire, as noo bones or other remains were found. folder with document - colored manila folders stock pictures, royalty-free photos & images. Tag series numbered from 0000-19999. I remember thinking, How could I spend this much time and not find anything?. In January of 1959, ten college students decided to go on a hiking trip in the Ural Mountains of the Soviet Union. The report may be based on politics or ignorance, but its not based on science, Kussman told the New York Times. If the children were kidnapped, they may not have come forward to protect the rest of their family from harm. That surreal night would throw Riverside General Hospital into newspapers and tv news broadcasts for weeks, as the frightening possibility of a human body releasing toxic fumes captured the publics imagination. Questions were immediately raised over how she made it to the locked rooftop and how she replaced the heavy lid from inside. Medical personnel think of sterile as being without bugs, not without chemicals, Andresen says. Shortly thereafter, Gorchynski began to feel nauseated. One of the most interesting theories is that Rivera was dropped through the roof of the hotel by a helicopter, possibly because of his work cleaning up the public image of his childhood friend Porter Stansberry. A relatively unassuming bridge in Scotland holds a dark secret that has haunted the city of Glasgow, Scotland for years. Sign up for our email newsletter for the latest science news, Want More? Others developed breathing problems and one nurse experienced paralysis - and no one knew why. Here finally was a chemical that could cause some real damage. But now add two oxygen atoms to dimethyl sulfone which in chemical notation is written (CH3)2SO2 and you get dimethyl sulfate, (CH3)2SO4, a truly nasty chemical. The investigation into her death, Hill said, was finished. Her heart was beating too rapidly to allow its chambers to fill before they pumped, so her blood pressure was plummeting. Weve never said this is what happened, just that people should look into it. Complaining that she was lightheaded, she left the trauma room and sat at a nurse's desk. It was so bizarre that it inspired episodes in many TV shows, including The X-Files, Greys Anatomy, The New Detectives, and Law & Order. The Riverside Coroner's Office hailed Livermore's DMSO conclusion as the probable cause of the hospital workers' symptoms, while her family disagreed. It contained a photo with a strong resemblance to him, but the lead went nowhere. Stanley Jacob, a physician and medical researcher at the Oregon Health Sciences University in Portland, doubts that significant quantities of the suspect chemicals could have been produced from dmso. By the time she got to the emergency room, she was in a confused state and already suffering from abnormal heart rate and breathing. A search of his house turned up a bizarre note taped to the back of his computer, which contained quotes from Freemason texts, lists of movie titles, and names of Hollywood figures. So far, all the suspects have beaten the rap, except for one extraordinary hypothesis: a team of researchers think that a chain of chemical reactions may essentially have turned Gloria Ramirezs body into a canister of nerve gas. One reference was particularly enlightening, if grisly a classified Department of Defense document, issued in 1987, called the Reference Book on Chemical Warfare Information. This WWII Shipwreck Is Pouring Pollutants Into The North Sea. Micozzi is a forensic pathologist who has helped investigate dozens of unusual deaths. This is where we were afraid we might find a showstopper that would kill the theory, says Grant. By studying the mass spectra, Andresen divined the identity of a number of compounds that had been circulating in Ramirezs system just before her death; among them were the drugs lidocaine, Tylenol, codeine, and Tigan, an antinausea medication. Kane turned toward the door of the trauma room and swayed. In DMSO2 form, it is known to crystallize at room temperature, which could explain the manila-colored crystals the blood that was drawn from her body (at 98.6 0F) and into the syringe (at room temperature, 64 0F). The worlds only Antarctic murder mystery remains unsolved. Im a nuclear chemist, and my organic chemistry knowledge truthfully is minuscule, he says. At 8:50p.m., after 45 minutes of CPR and defibrillation, Ramirez was pronounced dead from kidney failure related to her cancer. Yuri Yudin stated that he believed there was an explosion, possibly from a weapons test, and cover-up by the Soviet military. The incident was initially considered to be a case of mass hysteria. He also highlighted the findings that had intrigued him: the amine that might have caused the ammonia-like odor, the nicotinamide, and the dimethyl sulfone. Ignoring the red herrings, Andresen found a few interesting anomalies. Shop Now LRV 68.26 Collection Color Preview Get your own digital color dollop of Manila 2158-50 Create My Dollop Lighting Screen colors may differ. The most commonly discussed explanation for the death is that Lam suffered a mental health crisis. The plan they developed was straightforward: analyze the compounds, both organic and inorganic, in the blood, bile, and tissues from Ramirezs organs, including her heart, liver, lungs, brain, and kidneys. The parents of the trip leader Igor Dyatlov also agreed that the military was involved in hiding the students deaths. Find the latest trending videos, discover original shows and checkout what's going on with your favorite creators. The standard model is the name given in the 1970s to a theory of fundamental particles and how they interact. However, Osorio and Waller did not rule out the possibility that some substance poisoned emergency room staff who had worked directly over Ramirez. Soviet authorities investigated and decided that six died from hypothermia and three from trauma. Then came the pathologists from Riverside Coroners Office who took samples of blood, tissue, and air from the body bag and aluminum crate in which Ramirezs body was held. They shot through two sets of double glass doors, veered to their left, and parked her in a small curtained space marked trauma room one. However, the autopsies never presented definitive reasons for Ramirezs strange ailments and why several of the hospital staffers fell mysteriously ill. In 2016, diplomatic staff in Cuba began to experience a strange illness. Welch, meanwhile, forced air into Ramirezs lungs with an Ambu-bag, a football-size rubber bladder connected to a plastic mask thats placed over the patients nose and mouth, serving as a sanitary alternative to mouth-to-mouth resuscitation. Even if Ramirez had applied DMSO to her body to ease her pain, however, and even if it had combined with oxygen to form the dimethyl sulfone Andresen had found, that still didnt explain the outbreak among the hospital staff. Colored particles are bound together by the appropriately named gluons. The roof above Riveras body had a small hole that suggested he had smashed through at an almost vertical angle, but there was no clear area he could have jumped from. A staff member asked her if she was okay, but before she could respond she also fainted. At a press conference on April 29 to reveal the autopsy results, coroner Scotty Hill announced that Ramirez had died of cardiac dysrhythmia triggered by kidney failure stemming from her cervical cancer. Image Source: brantford Top 10 Creepy Mysteries From The American South. The Ramirez family's pathologist was unable to determine a cause of death because her heart was missing, her other organs were cross-contaminated with fecal matter, and her body was too badly decomposed. The REDSTONE, SPELL_MOB and SPELL_MOB_AMBIENT particles can also use custom colors by providing some specific data when spawning them. Only 1 left in stock - order soon. Facebook Watch is the place to enjoy videos and shows together. At this point, Kane fainted and was removed from the room. YouTubeGloria Ramirez, before her 1994 death. Catch her! Though there was nothing unusual about her except for being too young, the incident that followed her admittance to the emergency room baffled the doctors and researchers. What had been (CH3)2SO2 became CH3, CH3, and SO2. This urban legend, similar to the Bloody Mary mirror game, involves pressing elevator buttons in a certain order to travel to a different dimension. Using a standardized questionnaire, Osorio and Waller found that the people who had developed severe symptoms such as loss of consciousness, shortness of breath, and muscle spasms tended to have certain things in common. At this point, Kane fainted and was removed from the room. Other precursors of dimethyl sulfate, like sulfur-bearing amino acids, probably couldnt produce enough of the chemical to wreak so much havoc. Finally, the electric shocks during defibrillation could have converted DMSO2 to DMSO4, exposure to which could have caused the symptoms among those who were in the vicinity. Residents speculated that it could be human waste dumped from passing planes, which could explain why it made people sick, but airlines quickly disputed this because plane waste is dyed blue. On April 20, 1994ten weeks after her deathRamirez was buried at Olivewood Memorial Park in Riverside. None of the hospital staff reported tearing or other eye irritation. 1 part Manila Colored Inventory Tag - Plain. The county health department called in Californias Department of Health and Human Services, which put two of its top scientists on the case, Doctors Ana Maria Osorio and Kirsten Waller. This material-related article is a stub. Since DMSO can react with oxygen and form dimethyl sulfone, Grant began to wonder what other compounds might be formed when oxygen is added to the chemical. In real blood those crystals might have appeared manila-colored. Multiple calls to the fire department did not get through. When youre exposed to dimethyl sulfate vapors, the first thing that happens is it makes you start to cry. You will need to use the method Player.spawnParticle which takes the full set of available . The nurse who drew the blood quickly fainted, and soon two other people in the room passed out. Several organic chemists have scoffed at the step-by-step change of DMSO into airborne dimethyl sulfate. This hunting desire could combine with the layout of the bridge and the surrounding plant life to give the appearance of solid ground, confusing the animals into thinking there is no drop off. It was later discovered that she was being treated for bipolar disorder, but had it under control for several years. When they tried to draw blood from her arm, they noticed an ammonia-like smell coming from the tube and manila-colored particles in her blood. 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